BALTIMORE—Gunnar Henderson provided the offense with one swing and Corbin Burnes provided the pitching with seven strong innings to lead the Orioles to a 6-1 win over the Boston Red Sox before 18,857 at Camden Yards on Wednesday night.

Burnes allowed one unearned run on three hits, and Henderson hit a grand slam to cap a five-run second inning.

Burnes (5-2) threw a season high 108 pitches, striking out five and walking three. It was the second time this season he’s gone seven innings, both against Boston (28-28).

Heading into an offday on Thursday, the Orioles (35-19) have won six of seven and are 13-0-5 in their last 18 series against American League East teams.

Henderson’s grand slam came against Boston starter Kutter Crawford (2-4). Ramón Urías’ RBI single scored Colton Cowser, and after James McCann punctuated his first walk of the season with a Henderson-like bat flip, Henderson followed with his 18^th home run of the season.

The Red Sox scored a run in the top of the second thanks to sloppy play by the Orioles. With one out, Connor Wong singled to left, and Cowser’s throw to second was wild, allowing Wong to reach second.

Burnes tried to pick Wong off second, but Henderson dropped the ball for a second error. Dominic Smith grounded the ball to second baseman Jorge Mateo, but his throw home wasn’t close to being on time, and Wong scored.

Burnes allowed a one-out single to Wilyer Abreu in the sixth and a bunt single to Wong in the seventh. After Burnes walked Vaughn Grissom with one out, pitching coach Drew French visited the mound, and Burnes finished his start by retiring David Hamilton on a fly to left and a strikeout of Ceddane Rafaela.

Danny Coulombe and Dillon Tate worked scoreless innings in relief of Burnes, and Urías hit his second home run in the eighth for a 6-1 lead.